Weight loss drug ETF bets big on Eli Lilly, Novo Nordisk

A top exchange-traded fund provider is betting on the long-term popularity of GLP-1 weight loss drugs.

Roundhill Investments’ GLP-1 & Weight Loss ETF (OZEM), which began trading last week, pairs leaders Eli Lilly and Novo Nordisk with players developing new treatments for weight loss and diabetes. CEO Dave Mazza said his firm is capitalizing on explosive growth potential in the industry.

“The ability to have active management to overweight companies that are actually in market producing the drugs and then go down the line to identify those that are in particular phases is powerful,” Mazza told CNBC’s “ETF Edge” last Monday.

Eli Lilly and Novo Nordisk each hold a roughly 20% weighting in the ETF, per Roundhill’s website as of Friday. The three next largest positions are Zealand Pharma, Amgen and Chugai Pharmaceutical, each of which have a weighting under 5%.

In the past year, Eli Lilly is up 90%, while Novo Nordisk has gained 68%, as of Friday’s market close. Mazza waived concerns that investors have missed out on the rally, noting the weight loss drug industry is still in its “early days.”

“The marketplace has plenty of room for growth with other companies coming in, whether they’re with more powerful drugs or with things that actually you don’t need to have an injectable.”

He also sees GLP-1 drugmakers following a similar trajectory to AI-linked stocks.

“It’s a little bit like thinking about Nvidia with AI. They just have a head start,” Mazza said. “[Eli Lilly and Novo Nordisk] pivoted to focus on diabetes and weight loss drugs a few years ago, were able to get in market and produce results that are remarkable.”

After last Tuesday’s launch, shares of Roundhill’s GLP-1 & Weight Loss ETF ended the week down by almost 2%.

Don’t miss these exclusives from CNBC PRO

  • Related Posts

    China keeps tight grip on rare earths, costing at least one company ‘millions of euros’

    Mineral explorers hoping to meet the growing demand for rare earths are vying for a slice of nearly $1 billion in Brazilian funding to help make their projects a reality…

    Treasury secretaries ‘have a history of dueling’

    Treasury Secretary Scott Bessent brushed off recent reports of heated arguments inside President Donald Trump’s administration, saying disputes were a part of the normal push-and-pull of policymaking. “Treasury secretaries dating…

    Leave a Reply

    Your email address will not be published. Required fields are marked *

    You Missed

    When should I seek legal advice for Workplace discrimination?

    • By admin
    • July 2, 2026
    • 34 views

    What is included in an adversarial assessment?

    • By admin
    • May 29, 2026
    • 50 views

    How can I win an unjust dismissal Canada case?

    • By admin
    • May 4, 2026
    • 47 views

    웹사이트 검색누락 키워드 넣어야 하나요?

    • By admin
    • April 21, 2026
    • 52 views

    좌석 종류는 강남달토가 다양한 편이야?

    • By admin
    • April 2, 2026
    • 46 views

    강남 가라오케 낮에도 열어요?

    • By admin
    • March 23, 2026
    • 57 views